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Registro Completo |
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
12/07/2018 |
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Data da última atualização: |
12/07/2018 |
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Tipo da produção científica: |
Artigo em Anais de Congresso |
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Autoria: |
FERNANDES, L. T.; ONO, R. K.; IBELLI, A. M. G.; LAGOS, E. B.; MORES, M. A. Z.; CANTAO, M. E.; LORENZETTI, W. R.; PEIXOTO, J. de O.; PEDROSA, V. B.; LEDUR, M. C. |
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Afiliação: |
LANA TEIXEIRA FERNANDES, CEDISA; RAFAEL KEITH ONO; ADRIANA MERCIA GUARATINI IBELLI, CNPSA; UEPG; MARCOS ANTONIO ZANELLA MORES, CNPSA; MAURICIO EGIDIO CANTAO, CNPSA; WILLIAM RAPHAEL LORENZETTI, UDESC/Chapecó; JANE DE OLIVEIRA PEIXOTO, CNPSA; VICTOR BRENO PEDROSA; MONICA CORREA LEDUR, CNPSA. |
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Título: |
Novel putative candidate genes associated with umbilical hernia in pigs. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 11., 2018, Auckland, New Zealand. Proceedings... Massey University, 2018. Digital Archive. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Umbilical hernia is one of the most frequent anatomical defects in pigs in which abdominal contents protrude through the umbilical ring. This condition is considered to have a multifactorial basis in which environmental, infectious and genetic factors play a role. However, a better understanding about the genetic components involved in the umbilical hernia development has not yet been achieved. Although a few studies have mapped QTL for umbilical hernia, just a few candidate genes were reported. Therefore, the aim of this study was to identify genomic regions related to the development of umbilical hernias in pigs and search for potential candidate genes. A GWAS was performed with 92 cases and 233 control crossbred pigs. Five SNPs were associated with umbilical hernia: on SSC4/SSC6/SSC13 and one with unknown position. Candidate genes TBX15 and WARS2 were identified close to the SNP on SSC4. Another two candidate genes were located near the SNP associated with umbilical hernia on SSC13 (LIPI and RBM11). Further validation of these genes should be performed to improve the knowledge about umbilical hernia development in order to improve pig welfare and production by eliminating susceptible animals through genetic selection Resumo: A hérnia umbilical é um dos defeitos anatômicos mais freqüentes em suínos nos quais o conteúdo abdominal se projeta através do anel umbilical. Considera-se que esta condição tem uma base multifatorial na qual fatores ambientais, infecciosos e genéticos desempenham um papel. Entretanto, um melhor entendimento sobre os componentes genéticos envolvidos no desenvolvimento da hérnia umbilical ainda não foi alcançado. Embora alguns estudos tenham mapeado o QTL para a hérnia umbilical, apenas alguns genes candidatos foram relatados. Portanto, o objetivo deste estudo foi identificar regiões genômicas relacionadas ao desenvolvimento de hérnias umbilicais em porcos e buscar potenciais genes candidatos. Um GWAS foi realizado com 92 casos e 233 porcos cruzados de controle. Cinco SNPs foram associados com hérnia umbilical: em SSC4 / SSC6 / SSC13 e um com posição desconhecida. Os genes candidatos TBX15 e WARS2 foram identificados próximos ao SNP em SSC4. Outros dois genes candidatos foram localizados perto do SNP associado à hérnia umbilical na SSC13 (LIPI e RBM11). A validação adicional desses genes deve ser realizada para melhorar o conhecimento sobre o desenvolvimento de hérnia umbilical, a fim de melhorar o bem-estar ea produção de suínos, eliminando os animais suscetíveis por meio da seleção genética MenosAbstract: Umbilical hernia is one of the most frequent anatomical defects in pigs in which abdominal contents protrude through the umbilical ring. This condition is considered to have a multifactorial basis in which environmental, infectious and genetic factors play a role. However, a better understanding about the genetic components involved in the umbilical hernia development has not yet been achieved. Although a few studies have mapped QTL for umbilical hernia, just a few candidate genes were reported. Therefore, the aim of this study was to identify genomic regions related to the development of umbilical hernias in pigs and search for potential candidate genes. A GWAS was performed with 92 cases and 233 control crossbred pigs. Five SNPs were associated with umbilical hernia: on SSC4/SSC6/SSC13 and one with unknown position. Candidate genes TBX15 and WARS2 were identified close to the SNP on SSC4. Another two candidate genes were located near the SNP associated with umbilical hernia on SSC13 (LIPI and RBM11). Further validation of these genes should be performed to improve the knowledge about umbilical hernia development in order to improve pig welfare and production by eliminating susceptible animals through genetic selection Resumo: A hérnia umbilical é um dos defeitos anatômicos mais freqüentes em suínos nos quais o conteúdo abdominal se projeta através do anel umbilical. Considera-se que esta condição tem uma base multifatorial na qual fatores ambientais, infecciosos ... Mostrar Tudo |
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Palavras-Chave: |
Candidate genes; Congenital defect; GWAS; Hérnia umbilical; Umbilical hernia. |
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Thesagro: |
Melhoramento Genético Animal; Suíno. |
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Thesaurus Nal: |
Animal genetic resources; Swine. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/179728/1/final8696.pdf
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Marc: |
LEADER 03630nam a2200325 a 4500
001 2093239
005 2018-07-12
008 2018 bl uuuu u00u1 u #d
100 1 $aFERNANDES, L. T.
245 $aNovel putative candidate genes associated with umbilical hernia in pigs.$h[electronic resource]
260 $aIn: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 11., 2018, Auckland, New Zealand. Proceedings... Massey University, 2018. Digital Archive.$c2018
520 $aAbstract: Umbilical hernia is one of the most frequent anatomical defects in pigs in which abdominal contents protrude through the umbilical ring. This condition is considered to have a multifactorial basis in which environmental, infectious and genetic factors play a role. However, a better understanding about the genetic components involved in the umbilical hernia development has not yet been achieved. Although a few studies have mapped QTL for umbilical hernia, just a few candidate genes were reported. Therefore, the aim of this study was to identify genomic regions related to the development of umbilical hernias in pigs and search for potential candidate genes. A GWAS was performed with 92 cases and 233 control crossbred pigs. Five SNPs were associated with umbilical hernia: on SSC4/SSC6/SSC13 and one with unknown position. Candidate genes TBX15 and WARS2 were identified close to the SNP on SSC4. Another two candidate genes were located near the SNP associated with umbilical hernia on SSC13 (LIPI and RBM11). Further validation of these genes should be performed to improve the knowledge about umbilical hernia development in order to improve pig welfare and production by eliminating susceptible animals through genetic selection Resumo: A hérnia umbilical é um dos defeitos anatômicos mais freqüentes em suínos nos quais o conteúdo abdominal se projeta através do anel umbilical. Considera-se que esta condição tem uma base multifatorial na qual fatores ambientais, infecciosos e genéticos desempenham um papel. Entretanto, um melhor entendimento sobre os componentes genéticos envolvidos no desenvolvimento da hérnia umbilical ainda não foi alcançado. Embora alguns estudos tenham mapeado o QTL para a hérnia umbilical, apenas alguns genes candidatos foram relatados. Portanto, o objetivo deste estudo foi identificar regiões genômicas relacionadas ao desenvolvimento de hérnias umbilicais em porcos e buscar potenciais genes candidatos. Um GWAS foi realizado com 92 casos e 233 porcos cruzados de controle. Cinco SNPs foram associados com hérnia umbilical: em SSC4 / SSC6 / SSC13 e um com posição desconhecida. Os genes candidatos TBX15 e WARS2 foram identificados próximos ao SNP em SSC4. Outros dois genes candidatos foram localizados perto do SNP associado à hérnia umbilical na SSC13 (LIPI e RBM11). A validação adicional desses genes deve ser realizada para melhorar o conhecimento sobre o desenvolvimento de hérnia umbilical, a fim de melhorar o bem-estar ea produção de suínos, eliminando os animais suscetíveis por meio da seleção genética
650 $aAnimal genetic resources
650 $aSwine
650 $aMelhoramento Genético Animal
650 $aSuíno
653 $aCandidate genes
653 $aCongenital defect
653 $aGWAS
653 $aHérnia umbilical
653 $aUmbilical hernia
700 1 $aONO, R. K.
700 1 $aIBELLI, A. M. G.
700 1 $aLAGOS, E. B.
700 1 $aMORES, M. A. Z.
700 1 $aCANTAO, M. E.
700 1 $aLORENZETTI, W. R.
700 1 $aPEIXOTO, J. de O.
700 1 $aPEDROSA, V. B.
700 1 $aLEDUR, M. C.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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Registro Completo
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
07/01/2009 |
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Data da última atualização: |
22/03/2023 |
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Tipo da produção científica: |
Artigo em Anais de Congresso |
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Autoria: |
SILVA, C. M. M. de S.; CASTRO, V. L. S. S. de; OLIVEIRA, P. R.; MAIA, A. de H. N. |
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Afiliação: |
Célia Maria Maganhotto de Souza Silva, Embrapa Meio Ambiente; VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; Pablo Roberto de Oliveira, Estagiário-Embrapa Meio Ambiente; ALINE DE HOLANDA NUNES MAIA, CNPMA. |
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Título: |
Influence of Pseudomonas putida AF7 inoculation on soil enzymes. |
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Ano de publicação: |
2008 |
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Fonte/Imprenta: |
In: EUROPEAN REMEDIATION CONFERENCE, 4., 2008, Chania, Greece. E-proceedings... Chania: Technical University of Crete, 2008. 4p. ID 259. |
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Idioma: |
Inglês |
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Conteúdo: |
Pseudomonas may use as bioremediator and as biopesticide. The use of soil enzymatic assays as biological indicator of possible negative effects in soil functioning was evaluated after P.putida AF7 inoculation. For that, AF7 was originally isolated from the rizosphere of rice and was inoculated on three soils: Rhodic Hapludox (RH), Typic Hapludox (TH); and Arenic Hapludult (AH). Soil characteristics were measured in each plot. Acid phosphatase, ?-glucosidase and protease activities were measured at 7, 14 and 21 days. The enzyme activity waved during the experimental period but there is a significant reduction of ?-glucosidase activity in RH soil on day 14. Corg was positively correlated to the activities of ?-glucosidase and protease. The presented data indicate that soil biochemical properties may be useful as indicator of soil perturbations. |
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Palavras-Chave: |
Bioremediação. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/145737/1/2008AA-102.pdf
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Marc: |
LEADER 01431nam a2200157 a 4500
001 1016083
005 2023-03-22
008 2008 bl uuuu u00u1 u #d
100 1 $aSILVA, C. M. M. de S.
245 $aInfluence of Pseudomonas putida AF7 inoculation on soil enzymes.$h[electronic resource]
260 $aIn: EUROPEAN REMEDIATION CONFERENCE, 4., 2008, Chania, Greece. E-proceedings... Chania: Technical University of Crete, 2008. 4p. ID 259.$c2008
520 $aPseudomonas may use as bioremediator and as biopesticide. The use of soil enzymatic assays as biological indicator of possible negative effects in soil functioning was evaluated after P.putida AF7 inoculation. For that, AF7 was originally isolated from the rizosphere of rice and was inoculated on three soils: Rhodic Hapludox (RH), Typic Hapludox (TH); and Arenic Hapludult (AH). Soil characteristics were measured in each plot. Acid phosphatase, ?-glucosidase and protease activities were measured at 7, 14 and 21 days. The enzyme activity waved during the experimental period but there is a significant reduction of ?-glucosidase activity in RH soil on day 14. Corg was positively correlated to the activities of ?-glucosidase and protease. The presented data indicate that soil biochemical properties may be useful as indicator of soil perturbations.
653 $aBioremediação
700 1 $aCASTRO, V. L. S. S. de
700 1 $aOLIVEIRA, P. R.
700 1 $aMAIA, A. de H. N.
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Embrapa Meio Ambiente (CNPMA) |
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